One of the best interviews done to date. Kevin McKernan is brave as hell. It was a pleasure to hear two men of science speak freely: younger tribe members: this is what the world used to be and what we have lost.
I don’t see how it is possible to quantify a “dose” when self-replicating mRNA is part of the equation. Because it seems logical there would or could be great variation in each person’s individual response based on their genetics and medical history, and as McKernan noted, presence or absence of certain diseases. Probably medication as well. And if you don’t know the amount of replication that will occur, or where in the body it will be expressed, you can’t understand what a dose is. Flinging it out into the world, especially with the possibility of shedding and acquired transmissibility seems a stupendously bad idea…
I won’t lie: this scared me a great deal. We’re not even at the point where we know what it is we know and what we don’t yet know. A little humility and and a lot of caution are in order, but these virtues are in short supply.